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Long COVID in Children and Teenagers

Long COVID in Children and Teenagers

The PostAcute Sequelae of SARSCoV-2 (PASC) The COVID-19 pandemic has caused widespread devastation, with the immediate and short-term effects of SARS-CoV-2 infection now well described. While most people recover, many experience longer-lasting effects known as long...

New WHO Guidance on Best Practices for Clinical Trials

New WHO Guidance on Best Practices for Clinical Trials

The clinical trial landscape has undergone significant changes since the concept of trials was first introduced, with notable shifts in the social, ethical, and regulatory environments worldwide. The Clinical Trial Landscape Is Evolving Today, there is a broader...

#CountAfricaIn: Strengthening the Clinical Research Ecosystem

#CountAfricaIn: Strengthening the Clinical Research Ecosystem

In recent years, the global landscape of clinical research (CR) has been evolving, with Africa emerging as a vital player in this field. Despite being home to a wealth of diverse populations and disease burdens, the continent remains underrepresented in clinical...

Precision Medicine: An Introduction to Umbrella and Basket Trials

Precision Medicine: An Introduction to Umbrella and Basket Trials

Example of a real umbrella trial. Study scheme of the lung cancer master protocol (Lung-MAP–NCT03851445) trial. From Ouma L.O. et al. (2022) Front. Med. 9:1037439. doi: 10.3389/fmed.2022.1037439 In recent decades, cancer treatment has evolved from relying on...